Gotu Kola Extract

Gotu kola is used for reducing fatigue, improving memory, venous insufficiency including varicose veins, circulation, wound healing, and increasing longevity. Gotu kola is also used for memory loss and as an aphrodisiac. The triterpenoid saponins in gotu kola seem to be involved in wound healing and decreasing venous pressure in venous insufficiency; asiaticoside and madecassoside have anti-inflammatory activity. There is also some evidence that asiaticosides might promote wound healing by stimulating collagen and glycosaminoglycan synthesis.

There is preliminary evidence that asiaticosides might also have preventive and therapeutic effects on gastrointestinal ulcers. Anti-ulcer mechanisms may be due to strengthening action on gastric mucosal lining and suppression of damaging effects of free radicals. There is preliminary evidence that gotu kola extracts might have sedative, anticonvulsant, and analgesic effects, possibly mediated in part via increased levels of the inhibitory transmitter, GABA .

Gotu kola extracts also seem to have antibacterial activity in vitro against various bacteria such as Pseudomonas pyocyaneus, Trichoderma mentagrophytes, and Entamoeba histolytica, and antiviral activity against herpes simplex type II. There is some interest in using gotu kola to treat cancer. Dried powder extracts of gotu kola exhibit cytotoxic and anti-tumor properties in preliminary studies. Normal lymphocytes are not harmed, which suggests gotu kola exerts selective toxicity towards tumor cells.

May be beneficial in aging, arteriosclerosis, depression, headaches, high blood pressure, hypoglycemia, fatigue, chronic venous insufficiency, sexual insufficiency, varicose veins and wound healing.

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